A sexually aggressive woman who's after a good lay in the sack! When there's good peen involved, man eaters never back down. She will chase your skivvies off the seams.
2.) A scandalous female, like that of a hussy or whore.
n. - (sometimes stylized as T.H.O.T.) 'That hoe over there'; a promiscuous woman. Usually the term is aimed at an evil bitch who is in ear shot to hear you exclaim, "I see you've picked up all the trash off the floor, but you forgot about thot!"